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SuperCoolPalmettoSuperCool™ Palmetto is a standardized and enhanced Saw Palmetto product for healthy prostate function and healthy hair follicles, attributes that promote well-being in a significant amount of men over  the age of 50 and increase with age [U.S. Patent Pending, 2003].

Chemical StructuresSuperCool™ Palmetto was developed by utilizing Aphios’ patented SuperFluids™ fractionation and manufacturing technologies. Saw palmetto as a dietary supplement most commonly consists of a hexane or ethanolic and, more recently, supercritical fluid extracts of the berries of the American Dwarf Palm Tree (Serenoa repens) located in Florida.

Dose Response Curves Scientists at Aphios utilized the inhibition of testosterone metabolism to dihydro-testosterone by 5-alpha reductase to identify bioactive fractions. Inhibition of this enzyme, 5-alpha reductase, correlates positively with prostate function and hair follicle health. As such, the inhibition of this enzyme may result in healthy prostate function as well as healthy hair follicles

Gas Chromatograms Phytosterols (campesterol, stigmasterol, ß-sitosterol and stigmastanol) content of these fractions were measured by gas chromatography. The highest level of bioactivity, as measured by 5-alpha reductase inhibition, was found in the bioactive fractions that had the highest phytosterol content. Phytosterols are thus used as secondary standard for SuperCool™ Palmetto.

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