Sunday, 20 May 2012
Wednesday, 04 August 2010 21:17
Surgery: Post-Operative Nausea and Vomiting (PONV)
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Recently, ginger has been studied scientifically for its effect on nausea and vomiting associated surgery (Pongrojpaw and Chiamchanya, 2003).
Although effects are promising, there have been inconsistencies as reported in a number of studies on PONV (Arfeen et al., 1995; Bone et al., 1990; Phillips et al., 1993; Visalyaputra et al., 1998).
Potential confounding factors in studies of PONV include the nausea-inducing effect of various anesthetics and short assessment periods, allowing little time for ginger to exert its maximum effects.
A meta-analysis of 5 randomized clinical trials (RCTs) including 363 patients found that a fixed dose of at least 1 g of powdered ginger is more effective than placebo in preventing PONV (Chaiyakunapruk, 2006).
References
Arfeen, Z. Owen, H. Plummer, J. L. Ilsley, A. H. Sorby-Adams, R. A., Doecke, C.J. (1995) A double-blind randomized controlled trial of ginger for the prevention of postoperative nausea and vomiting. Anaesth Intensive Care 23(4): 449-52.
Bone, M.E., Wilkinson, D. J. Young, J. R. McNeil, J., Charlton, S. (1990) Ginger root--a new antiemetic. The effect of ginger root on postoperative nausea and vomiting after major gynaecological surgery. Anaesthesia 45(8): p. 669-71.
Chaiyakunapruk, N. Kitikannakorn, N. Nathisuwan, S. Leeprakobboon, K., Leelasettagool, C. (2006) The efficacy of ginger for the prevention of postoperative nausea and vomiting: a meta-analysis. Am J Obstet Gynecol 194(1): 95-9.
Visalyaputra, S., Petchpaisit, N., Somcharoen, K., Choavaratana, R. (1998) The efficacy of ginger root in the prevention of postoperative nausea and vomiting after outpatient gynaecological laparoscopy. Anaesthesia 53(5): 506-10.
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