Wednesday, 22 Feb 2012
SuperCool™ St. John News
Wednesday, 04 August 2010 22:21
About SuperCool™ St. John
SuperCool™ St. John is an enhanced St. John's Wort product, which is standardized by hyperforin content [U.S. Patent No. 6,291,241 B1, Castor et al., 2001]. Additionally, Aphios utilized its patented SuperFluids™ fractionation and manufacturing technologies to develop this product.
Monday, 12 July 2004 22:46
Aphios Corporation Announces Launch of SuperCool™ St. John for Emotional Well-Being, Relaxed Outlook and Positive Mood
Woburn, Mass. — July 13, 2004 — Aphios Corporation today announced its launch of SuperCool™ St. John for feelings of well-being, relaxed outlook and positive mood.
SuperCool™ St. John is an advanced formulation of an enhanced hyperforin fraction of the flowers, buds and stems of St. John's Wort (Hypericum perforatum, SJW), a bushy perennial that blooms around St. John the Baptist day (June 24th). Aphios' SuperCool™ St. John product is standardized against hyperforins that show a linear dose response with serotonin reuptake inhibition [U.S. Patent No. 6,291,241B1, Castor et al., 2001]. Aphios' scientists and collaborators have shown that hyperforins are effective serotonin reuptake inhibitors (SRIs).
Tuesday, 23 October 2001 22:41
Aphios Corporation Granted United States Patent for Making an Enhanced St. John’s Wort Product
Woburn, Mass. — October 24, 2001 — Aphios Corporation announced today that it was granted United States Patent No. 6,291,241, entitled "Method for Making Hypericum Fractions and St. John's Wort Products," on September 18, 2001.
Wednesday, 10 May 2000 22:32
Aphios Corporation Awarded Phase II SBIR Grant from NCCAM, NIH for Improved St. John’s Wort Product
Woburn, Mass. — May 11, 2000 — Aphios Corporation has been awarded a Phase II SBIR grant from the National Center for Complementary and Alternative Medicine (NCCAM) of the National Institutes of Health (NIH) under their Fast Track Program. The grant is entitled “Method for Making an Improved St. John’s Wort Product.” St. John's Wort (Hypericum perforatum) is a bushy perennial with yellow flowers which blooms around St. John the Baptist's day (June 24th). An oil extract of the fresh flowers contains liposoluble napthodianthrones, such as hypericin and hyperforin. These compounds are thought to be responsible for St. John's reputation as an effective promoter of well-being.
Tuesday, 02 November 1999 22:29
Aphios Corporation Awarded Fast-Track SBIR Grant from NIH for Improved St. John’s Wort Product
Woburn, Mass. — November 03, 1999 — Aphios Corporation has been awarded a Fast-Track SBIR grant from the National Center for Complementary and Alternative Medicine (NCCAM) of the National Institutes of Health (NIH). The grant is entitled "Method for Making an Improved St. John’s Wort Product."
St. John's Wort (Hypericum perforatum) is a bushy perennial with yellow flowers which blooms around St. John the Baptist's day (June 24th). An oil extract of the fresh flowers contains liposoluble napthodianthrones, such as hypericin and hyperforin. These compounds are competitive monoamine oxidase inhibitors (MAOI), and are thought to be responsible for St. John's reputation as a promoter of well-being. Products, such as St. John’s Wort, are however being manufactured without any significant regard to the standardization, reproducibility and validity of the manufacturing process, or the content and quality of the active ingredients.
